New paper in Angew. Chem.

We have a new paper out in Angew. Chem.! Mosharraf and Josh show that carbodiimide-fueled anhydride formation can be used to assemble macrocycles containing multiple transient bonds. We believe this will have significant implications for generating out-of-equilibrium species of increased structural complexity.

Many thanks to the editors for selecting this as a “Hot Paper”!

New paper in Chem. Sci.

Our latest paper is out in Chemical Science! Zach and Viraj explore the interplay between folding and macrocyclization with ortho-phenylene hexamers and decamers. Confinement within the macrocycle forces the foldamer into conformations that are typically not observed, which is predictable using simple computational models.

MRI grant funded

Huge thanks to the NSF MRI program, which has funded a new NMR spectrometer for the department. This instrument will bring several new capabilities, including an autosampler (for greatly increased throughput of teaching and research samples), advanced 19F capabilities, and a flow accessory.