We have a new paper out in Angew. Chem.! Mosharraf and Josh show that carbodiimide-fueled anhydride formation can be used to assemble macrocycles containing multiple transient bonds. We believe this will have significant implications for generating out-of-equilibrium species of increased structural complexity.
Many thanks to the editors for selecting this as a “Hot Paper”!
Our latest paper is out in J. Org. Chem.! Lasith, Run, and our collaborators from the Sommer Group investigate structure–property effects in the assembly/disassembly of aqueous benzoic anhydrides fueled by carbodiimides.
Our latest paper is out in Chemical Science! Zach and Viraj explore the interplay between folding and macrocyclization with ortho-phenylene hexamers and decamers. Confinement within the macrocycle forces the foldamer into conformations that are typically not observed, which is predictable using simple computational models.
Our latest paper is out in J. Chem. Educ.! In collaboration with the Yezierski group, we have developed an undergraduate teaching lab on the self-assembly of macrocycles under thermodynamic control. The lab combined elements of experimental and computational chemistry to probe the importance of strain in these systems.
Our latest paper is out in Chem. Commun.! In collaboration with the Konkolewicz Group, we show that transient crosslinked polymer materials can be generated using carbodiimide-fueled carboxylic acid coupling.
Our latest paper is out in Chemical Science! We demonstrate twist-sense control in o-phenylenes by attaching various chiral imines. Close examination of structure–property effects gives a very detailed mechanism for this process.
Our latest paper is out in Org. Lett.! We show that simple changes to linker structure can be used to assemble ortho-phenylene-based macrocycles of different sizes and shapes.
Our latest paper is out in JACS. This is our first foray into nonequilibrium systems chemistry, where we show that carbodiimides are useful chemical fuels for dissipative covalent assembly.
Our latest paper is out in JACS. This work focuses on combining the folding of o-phenylenes with the assembly of macrocycles through dynamic covalent chemistry.
Our latest paper is out in Org. Biomol. Chem.! This work focuses on how solvent affects the folding of o-phenylenes.