We have a new paper out in Angew. Chem.! Mosharraf and Josh show that carbodiimide-fueled anhydride formation can be used to assemble macrocycles containing multiple transient bonds. We believe this will have significant implications for generating out-of-equilibrium species of increased structural complexity.
Many thanks to the editors for selecting this as a “Hot Paper”!
Our latest paper is out in J. Org. Chem.! Lasith, Run, and our collaborators from the Sommer Group investigate structure–property effects in the assembly/disassembly of aqueous benzoic anhydrides fueled by carbodiimides.
Welcome to new graduate students Renuka Baral and Andrew Miller and new undergraduate Nadeen Saleh!
Welcome to Will Carson and Griffin Betz, who have joined the group as undergraduate researchers!
Welcome to undergraduates Meng Gu, Sean Ginn, Kiley Blachaniec, and Kaitlyn Flynn, who have joined the group!
Our latest paper is out in Chemical Science! Zach and Viraj explore the interplay between folding and macrocyclization with ortho-phenylene hexamers and decamers. Confinement within the macrocycle forces the foldamer into conformations that are typically not observed, which is predictable using simple computational models.
Huge thanks to the NSF MRI program, which has funded a new NMR spectrometer for the department. This instrument will bring several new capabilities, including an autosampler (for greatly increased throughput of teaching and research samples), advanced 19F capabilities, and a flow accessory.
Welcome to Kate Bradford, who as joined the group as a graduate student! Kate is a member of both our group and the Konkolewicz group.