Author: Scott

A new paper is out in Angew. Chem.! Lasith and Mosharraf review the transient covalent bond as a tool for designing nonequilibrium systems, including molecular machines and dissipative assemblies.

We have a new paper out in Org. Lett.! Isuru, Frank, Georgia, and Lasith show that diphenic acid derivatives undergo transient geometry changes on treatment with carbodiimide fuels.

A new paper is out in Eur. J. Org. Chem.! Viraj and our collaborators Briana Schrage and Chris Ziegler from the University of Akron study the assembly of hydrocarbon o-phenylene macrocycles assembled using olefin metathesis. We continue to learn more and more about assembling foldamers into more complex structures, and the molecules are particularly pretty.

We have a new paper out in Angew. Chem.! Mosharraf and Josh show that carbodiimide-fueled anhydride formation can be used to assemble macrocycles containing multiple transient bonds. We believe this will have significant implications for generating out-of-equilibrium species of increased structural complexity.

Many thanks to the editors for selecting this as a “Hot Paper”!

Our latest paper is out in J. Org. Chem.! Lasith, Run, and our collaborators from the Sommer Group investigate structure–property effects in the assembly/disassembly of aqueous benzoic anhydrides fueled by carbodiimides.

Our latest paper is out in Chemical Science! Zach and Viraj explore the interplay between folding and macrocyclization with ortho-phenylene hexamers and decamers. Confinement within the macrocycle forces the foldamer into conformations that are typically not observed, which is predictable using simple computational models.